MASSIVELY PARALLEL REPORTER ASSAY CONFIRMS REGULATORY POTENTIAL OF HQTLS AND REVEALS IMPORTANT VARIANTS IN LUPUS AND OTHER AUTOIMMUNE DISEASES

Massively parallel reporter assay confirms regulatory potential of hQTLs and reveals important variants in lupus and other autoimmune diseases

Summary: We designed a massively Nutmeg parallel reporter assay (MPRA) in an Epstein-Barr virus transformed B cell line to directly characterize the potential for histone post-translational modifications, i.e., histone quantitative trait loci (hQTLs), expression QTLs (eQTLs), and variants on systemic lupus erythematosus (SLE) and autoimmune (AI) di

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Prevalence of auditory changes in newborns in a teaching hospital

Introduction: The precocious diagnosis and the intervention in the deafness are of basic importance in the infantile development.The loss auditory and more prevalent than other joined riots to the birth.Objective: Esteem the prevalence of auditory alterations in just-born in a hospital school.Method: Prospective transversal study that evaluated 226

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